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Knowledge base

Principelle IF

Principelle IF® is a sterile wound dressing, comprising an inert acetate substrate impregnated with an ointment containing a blend of trace elements and medical grade honey... Read more »

Product files

  • Product brochure (English), also available in Dutch, French, Italian and Spanish
  • Instructions for Use Principelle IF Dressings
  • Instructions for Use Principelle IF Ointment
  • Wound classification model

Case reports

  • Case Report Principelle IF
  • Case Report Principelle IF ointment, Principelle Matrix and MelMax
  • Case Report Principelle IF, MelMax and Principelle Matrix
  • Case Report Principelle IF and Principelle Matrix
  • Case Report MelMax & Principelle IF (Veterinary use)

Relevant literature

  • The Rediscovery of Honey for Skin Repair: Recent Advances in Mechanisms for Honey-Mediated Wound Healing and Scaffolded Application Techniques – Angioi 2021
  • Research Report Antibacterial Activity of Principelle IF ointment
  • Mechanism of honey bacteriostatic action against MRSA – Brudzynski 2013
  • Honey exposure stimulates wound repair of human dermal fibroblasts – Ranzato 2013
  • Powerful bacterial killing by buckwheat honeys – Brudzynski 2012
  • The evidence and the rationale for the use of honey as a wound dressing – Molan 2011
  • Are all wound products created equally? The re-emergence of natural honey – Al-Lenjawi 2015
  • An in vitro examination of the antioxidant and anti-inflammatory properties of buckwheat honey – Van den Berg 2008
  • The significance of surface pH in chronic wounds – Gethin 2007
  • The Evidence Supporting the use of honey as a wound dressing – Molan 2006
  • A clinical prospective study assessing the efficacy of a fenolic rich honey and PHI-5 dressing in therapy resistant and colonized burn defects – Hoeksema 2005
  • Clinical usage of honey as a wound dressing, an update – Molan 2004
  • The Effect of Dilution on the Rate of Hydrogen Peroxide Production in Honey and Its Implications for Wound Healing – Bang 2003
  • Potential of Honey in Treatment of Wounds and Burns – Molan 2001
  • Methylglyoxal – A Potential Risk Factor of Manuka Honey in Healing of Diabetic Ulcers – Majtan 2009

Product pictures, packshots & artwork

MelMax wound dressing
Medical Grade Dark Buckwheat Honey (Pelsan+ only)
Principelle IF ointment and dressing


Principelle IF 8×20 cm
Principelle IF 8×10 cm
Principelle IF 5×6 cm


Application (1)
Application (2)
Application (3)


Principelle IF 8×10 cm pouch
Principelle IF 8×20 cm pouch


Principelle Matrix

Principelle Matrix is a next generation sterile composite hydrogel wound dressing. Its design is based on a naturally occurring bioactive process... Read more »

Product files

  • Product brochure (English), also available in German, Italian, Portugese and Spanish
  • Product folder (English)
  • Instructions for Use Principelle Matrix
  • Wound classification model

Case reports

  • Case Report Principelle Matrix and MelMax
  • Case Report Principelle Matrix, MelMax and Principelle IF ointment
  • Case Report Principelle Matrix, MelMax and Principelle IF ointment
  • Case Report Principelle Matrix and Principelle IF ointment

Relevant literature

  • EWMA Poster Abstracts Principelle Matrix
  • EWMA Poster Principelle Matrix

Product pictures, packshots & artwork




MelMax

MelMax® is a sterile, inert wound dressing impregnated with a metal-ion formulation and medical grade buckwheat honey specifically selected for medical use. The blend of trace elements... Read more »

Product files

  • Product Brochure MelMax (English), also available in Dutch, French, German, Italian, Portugese and Spanish
  • Instructions for Use MelMax
  • Wound classification model

Case reports

  • Case Report Principelle IF ointment, Principelle Matrix and MelMax
  • Case Report Principelle IF, MelMax and Principelle Matrix
  • Case Report MelMax
  • Case Report Principelle Matrix and MelMax
  • Case Report MelMax & Principelle IF (Veterinary use)
  • Case Report MelMax (Veterinary use)

Relevant literature

  • Tissue viability research on MelMax
  • Mechanism of honey bacteriostatic action against MRSA – Brudzynski 2013
  • Honey exposure stimulates wound repair of human dermal fibroblasts – Ranzato 2013
  • Powerful bacterial killing by buckwheat honeys – Brudzynski 2012
  • The evidence and the rationale for the use of honey as a wound dressing – Molan 2011
  • Are all wound products created equally? The re-emergence of natural honey – Al-Lenjawi 2015
  • An in vitro examination of the antioxidant and anti-inflammatory properties of buckwheat honey – Van den Berg 2008
  • The significance of surface pH in chronic wounds – Gethin 2007
  • The Evidence Supporting the use of honey as a wound dressing – Molan 2006
  • A clinical prospective study assessing the efficacy of a fenolic rich honey and PHI-5 dressing in therapy resistant and colonized burn defects – Hoeksema 2005
  • Clinical usage of honey as a wound dressing, an update – Molan 2004
  • The Effect of Dilution on the Rate of Hydrogen Peroxide Production in Honey and Its Implications for Wound Healing – Bang 2003
  • Potential of Honey in Treatment of Wounds and Burns – Molan 2001
  • Methylglyoxal – A Potential Risk Factor of Manuka Honey in Healing of Diabetic Ulcers – Majtan 2009

Product pictures, packshots & artwork

MelMax wound dressing
MelMax wound dressing
Medical Grade Dark Buckwheat Honey (Pelsan+ only)


MelMax 5×6 cm box
MelMax 8×10 cm box
MelMax 8×20 cm box


MelMax 5×6 pouch
MelMax 5×6 pouch
MelMax 5×6 pouch


Pelsan and Pelsan+

Pelsan is a skin regeneration cream developed specially for dehydrated skin resulting from heat and sun exposure, or after radiation or laser therapy. Pelsan does... Read more »

Product files

  • Product Brochure Pelsan, also available in French, German, Italian and Portugese
  • Product flyer Pelsan+, also available in Portugese
  • Instructions for Use Pelsan
  • Instructions for Use Pelsan+
  • Product classification model

Case reports

  • Case Report Pelsan+
  • (Dutch) Case Report Matrix and Pelsan

Relevant literature

  • Effect of Pelsan cream on skin epithelial revitalisation during radiotherapy
  • Honey exposure stimulates wound repair of human dermal fibroblasts – Ranzato 2013
  • Mechanism of honey bacteriostatic action against MRSA – Brudzynski 2013
  • Powerful bacterial killing by buckwheat honeys – Brudzynski 2012
  • An in vitro examination of the antioxidant and anti-inflammatory properties of buckwheat honey – Van den Berg 2008
  • A clinical prospective study assessing the efficacy of a fenolic rich honey and PHI-5 dressing in therapy resistant and colonized burn defects – Hoeksema 2005

Product pictures, packshots & artwork

Pelsan+ (30 gram) tube
Pelsan (150 ml) pump


Pelsan+ (75 ml) pump
Pelsan (75 ml) box
Pelsan (150 ml) box


Medical Grade Dark Buckwheat Honey (Pelsan+ only)


Celan

Celan® is a medical grade honey based skin care ointment which contains active herbal ingredients with proven biological activity. For superficial... Read more »

Product files

  • Product Brochure Celan, also available in Italian, Portugese, Spanish, Turkish and French
  • Instructions for Use Celan
  • Product classification model

Case reports

  • Case Report Celan

Relevant literature

  • Honey exposure stimulates wound repair of human dermal fibroblasts – Ranzato 2013
  • Mechanism of honey bacteriostatic action against MRSA – Brudzynski 2013
  • Powerful bacterial killing by buckwheat honeys – Brudzynski 2012
  • An in vitro examination of the antioxidant and anti-inflammatory properties of buckwheat honey – Van den Berg 2008
  • A clinical prospective study assessing the efficacy of a fenolic rich honey and PHI-5 dressing in therapy resistant and colonized burn defects – Hoeksema 2005

Product pictures, packshots & artwork


Knowledge base

  • Principelle IF
  • Principelle Matrix
  • MelMax
  • Pelsan and Pelsan+
  • Celan
© Principelle B.V.

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